Mapping regions in Ste5 that support Msn5-dependent and -independent nuclear export
نویسندگان
چکیده
منابع مشابه
Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.
The Fanconi anemia (FA) pathway plays an important role in maintaining genomic stability, and defects in this pathway cause cancer susceptibility. The FA proteins have been found to function primarily in a nuclear complex, although a cytoplasmic localization and function for several FA proteins has also been reported. In this study, we investigated the possibility that FANCA, FANCC and FANCG ar...
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The Rev protein of HIV-1 actively shuttles between nucleus and cytoplasm and mediates the export of unspliced retroviral RNAs. The localization of shuttling proteins such as Rev is controlled by the relative rates of nuclear import and export. To study nuclear export in isolation, we generated cell lines expressing a green fluorescent protein-labeled chimeric protein consisting of HIV-1 Rev and...
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Pre-mRNAs are associated with hnRNPs, and these proteins play important roles in the biogenesis of mRNAs. The hnRNP A1 is one of the most abundant hnRNPs, and although localized primarily in the nucleoplasm, shuttles continuously between the nucleus and the cytoplasm. A 38 amino acid domain within A1, termed M9, which bears no resemblance to classical nuclear localization signal (NLS) sequences...
متن کاملCRM1- and Ran-independent nuclear export of β-catenin
Background: Activation of the Wnt pathway induces -catenin to localize Address: Max-Planck-Institute for Developmental Biology, Department of Cell Biology, Tübingen inside the nucleus, where it interacts with transcription factors such as D-72076, Germany. TCF/LEF-1. Regulation of the pathway occurs through a -catenin– degrading complex based on Axin and the tumor suppressor APC. We have Corres...
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ژورنال
عنوان ژورنال: Biochemistry and Cell Biology
سال: 2016
ISSN: 0829-8211,1208-6002
DOI: 10.1139/bcb-2015-0101